BACKGROUND: Genetic analysis in the mouse revealed that GREMLIN1 (GREM1)-mediated antagonism of BMP4 is essential for ureteric epithelial branching as the disruption of ureteric bud outgrowth and renal agenesis in Grem1-deficient embryos is restored by additional inactivation of one Bmp4 allele. Another BMP ligand. BMP7. was shown to control the proliferative expansion of nephrogenic ... https://www.roneverhart.com/The-Office-Pop-Vinyl-Figure-Fun-Run-Dwight-1394/
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